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Excerpts from:

Roholm K. (1937). Fluoride intoxication: a clinical-hygienic study with a review of the literature and some experimental investigations. London: H.K. Lewis Ltd.

"The teeth may be delayed in eruption and have abnormalities in size, shape and position, and resistance of such teeth is low." p. 272

"In the mild degrees [of dental fluorosis] the strength of the tooth does not seem to be reduced and the caries frequency is not remarkably high. In the severe degrees the enamel is brittle and the tooth as a whole little resistant." p. 290

"The pathological enamel is brittle and readily chips off. The incisors wear down abnormally, which sometimes leads to defective occlusion and, as a secondary phenomenon, abnormal growth of opposing teeth. The incisors often exhibit lateral deviations; growth is retarded." p. 272

"It has never been demonstrated, nor is it probable, that fluorine in phsyiological doses is necessary to or has a beneficial effect on the development of the teeth." p. 317

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